Overview
The FAIR Biomedical Research Software (FAIR-BioRS) guidelines are a set of minimal and actionable step-by-step guidelines for making biomedical research software FAIR (Findable, Accessible, Interoperable, Reusable), in line with the FAIR Principles for Research Software (FAIR4RS Principles).
What are research software?
Research software is any software created during the research process or for a research purpose. It can come in many format such as artificial intelligence (AI) models as Python scripts or data visualization tools as Jupyter notebooks. They are an essential aspects of biomedical research and therefore making them FAIR, i.e. optimally reusable is critical just like data.
How to make research software FAIR?
The FAIR Principles for Research Software (FAIR4RS Principles) are reformulated versions of the FAIR Principles developed by the research software community specifically to make research software reusable.
What are the challenges?
By design, the FAIR4RS Principles only provide a high-level framework for making software FAIR but do not provide practical instructions to do so. Therefore, making software FAIR requires an in-depth understanding of each of the FAIR4RS Principles, and finding out how to practically comply with them.
How do the FAIR-BioRS guidelines help?
We established the FAIR Biomedical Research Software (FAIR-BioRS) guideline, which are clear, actionable, and step-by-step guidelines for making biomedical research software FAIR. Researchers can simply follow and implement the guidelines as they are developing their software to make it compliant with the FAIR4RS principles.
Development Approach
The FAIR-BioRS guidelines were developed in collaboration with researchers from UCSF and ELIXIR (E.U.). We first established a list of outstanding questions we identified for practically implementing the FAIR4RS Principles (e.g., How to obtain a unique identifier for software? How to include metadata? and so on). Then we combined literature review, community feedback, and our own assessment as developers of research software to established answers for these questions. Finally, we organized these answers as a set of step-by-step instructions that follow the typical sofware development process which became the FAIR-BioRS guidelines.
Funding
The FAIR-BioRS guidelines were conceived while working on a project funded through a supplemental award from the National Institute of Allergy and Infectious Diseases (NIAID). Besides some initial effort through this project for the first few months, the development of the guidelines has been done without any support, through the sole will of the project members to make it easier for our peers wanting to develop and share FAIR software.
Team
Members
Researchers, engineers, and collaborators behind this project.
Research partners
The FAIR-BioRS guidelines were developed in collaboration with Dr. Zicheng Hu (UCSF) and Dr. Hervé Ménager (Institut Pasteur, ELIXIR).
Timeline
Milestone 5
Promotion and development of user support tools
September 2023 - Present
Impact related to this project
Showing 3 publications
- 2023Journal Articles
Patel, B., Soundarajan, S., Ménager, H., & Hu, Z. (2023). Making Biomedical Research Software FAIR: Actionable Step-by-step Guidelines with a User-support Tool. Scientific Data, 10(1). https://doi.org/10.1038/s41597-023-02463-x
- FAIR-BioRS: Actionable guidelines for making biomedical research software FAIR
Slides presented at Intelligent Systems for Molecular Biology (ISMB) 2023 and Bioinformatics Open Source Conference (BOSC) 2023
2023Conference PresentationsPatel, B., Soundarajan, S., Ménager, H., & Hu, Z. (2023). FAIR-BioRS: Actionable guidelines for making biomedical research software FAIR. F1000 Research Limited. https://doi.org/10.7490/f1000research.1119609.1
- FAIR-BioRS: Actionable guidelines for making biomedical research software FAIR
Poster presented at Intelligent Systems for Molecular Biology (ISMB) 2023 and Bioinformatics Open Source Conference (BOSC) 2023
2023PostersPatel, B., Soundarajan, S., Ménager, H., & Hu, Z. (2023). FAIR-BioRS: Actionable guidelines for making biomedical research software FAIR. F1000 Research Limited. https://doi.org/10.7490/f1000research.1119608.1


